TY - JOUR T1 - Intracranial Stent Placement for Recanalization of Acute Cerebrovascular Occlusion in 32 Patients JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 1222 LP - 1225 DO - 10.3174/ajnr.A2055 VL - 31 IS - 7 AU - J.S. Bang AU - C.W. Oh AU - C. Jung AU - S.Q. Park AU - K.J. Hwang AU - H.-S. Kang AU - M.H. Han AU - S.H. Lee AU - Y.S. Chung AU - O.-K. Kwon Y1 - 2010/08/01 UR - http://www.ajnr.org/content/31/7/1222.abstract N2 - BACKGROUND AND PURPOSE: Stents have been reported as an option for improvement of the recanalization rate in AIS. The authors have also used intracranial stents in failed cases of IAT with pharmacologic and mechanical methods since 2004. We retrospectively reviewed our cases of intracranial stent use for IAT of AIS for recanalization and as a rescue procedure for iatrogenic intracranial vascular dissection during IAT. MATERIALS AND METHODS: Thirty-two patients, who were diagnosed with AIS, were treated with intracranial stents (28 balloon-mounted and 7 self-expandable stents) at our neurovascular center between April 2004 and December 2008. The stent use for all 32 patients was the final attempt to recanalize occluded vessels after various trials of pharmacologic or mechanical thrombolysis or to treat iatrogenic vascular dissection. RESULTS: Among the 32 patients, immediate poststenting angiographic recanalization was achieved in 100% with TIMI/TICI 2 (15 of 32 lesions, 46.9%) or TIMI/TICI 3 (17 of 32 lesions, 53.1%). However, complication rates were also high. Major symptomatic intracerebral hemorrhage (1 case of procedural symptomatic hemorrhage and 3 cases of delayed symptomatic hemorrhage) occurred in 4 (12.5%); intracranial vascular dissection, in 4 (12.5%); extracranial vascular dissection, in 3 (9.4%); immediate IST, in 4 (12.5%); subacute (within 1 week) IST, in 2; late (>1 week) IST, in 1, and 1 case of in-stent restenosis occurred twice (at 5 and 17 months). CONCLUSIONS: Intracranial stent placement for AIS management has an excellent recanalization rate. However, it is associated with high complication risks as our series showed. We believe that the decision to treat AIS with intracranial stent placement should be made after careful consideration of potential benefits and risks. ACAanterior cerebral arteryAISacute ischemic strokeBAbasilar arteryDWIdiffusion-weighted imagingFLAIRfluid-attenuated inversion recoveryGp IIb-IIIa RBglycoprotein IIb-IIIa receptor blockerGREgradient recalled-echoIATintra-arterial thrombolysisICAinternal carotid arteryICHintracerebral hemorrhageISTin-stent thrombosisIVintravenousIV-tPAintravenous tissue plasminogen activatorMCAmiddle cerebral arterymRSmodified Rankin ScaleNIHSSNational Institutes of Health Stroke ScaleSx Hemosymptomatic hemorrhageTT occlusionTIMI/TICIThrombolysis in Myocardial Ischemia/Thrombolysis in Cerebral IschemiaUKurokinaseVAvertebral arteryVBAvertebrobasilar artery ER -