TY - JOUR T1 - Temozolomide (Temodar) JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 1383 LP - 1384 DO - 10.3174/ajnr.A2170 VL - 31 IS - 8 AU - J.R. Wesolowski AU - P. Rajdev AU - S.K. Mukherji Y1 - 2010/09/01 UR - http://www.ajnr.org/content/31/8/1383.abstract N2 - SUMMARY: Temozolomide, an oral alkylating agent, is a commonly used medicine in the treatment of anaplastic astrocytoma and glioblastoma multiforme. This paper will present the mechanism of action as well as the clinical role for this chemotherapeutic drug. FDAUS Food and Drug AdministrationMTICmethyl triazeno imidazole carboxamide ER -