PT  - JOURNAL ARTICLE
AU  - S. Kular
AU  - H. Holmes
AU  - A. Hart
AU  - P. Griffiths
AU  - D. Connolly
TI  - Evaluation of the Prevalence of Punctate White Matter Lesions in a Healthy Volunteer Neonatal Population
AID  - 10.3174/ajnr.A7578
DP  - 2022 Aug 01
TA  - American Journal of Neuroradiology
PG  - 1210--1213
VI  - 43
IP  - 8
4099  - http://www.ajnr.org/content/43/8/1210.short
4100  - http://www.ajnr.org/content/43/8/1210.full
SO  - Am. J. Neuroradiol.2022 Aug 01; 43
AB  - SUMMARY: Hypoxic-ischemic injury is the most common cause of neonatal encephalopathy. T1-weighted punctate white matter lesions have been described in hypoxic-ischemic injury. We have reviewed a healthy volunteer neonatal population to assess the prevalence of punctate white matter lesions in neonates with no clinical signs of hypoxic-ischemic injury. Fifty-two subjects were scanned on a neonatal-specific 3T MR imaging scanner. Twelve patients were excluded due to the lack of T1-weighted imaging, leaving a total of 40 patients (35 term, 5 preterm) assessed in the study. One had a solitary T1-punctate white matter lesion. We concluded that solitary punctate white matter lesions have a low prevalence in healthy neonates.HIIhypoxic-ischemic injuryPWMLpunctate white matter lesionSDHsubdural hematoma