TY - JOUR T1 - Evaluation of the Prevalence of Punctate White Matter Lesions in a Healthy Volunteer Neonatal Population JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 1210 LP - 1213 DO - 10.3174/ajnr.A7578 VL - 43 IS - 8 AU - S. Kular AU - H. Holmes AU - A. Hart AU - P. Griffiths AU - D. Connolly Y1 - 2022/08/01 UR - http://www.ajnr.org/content/43/8/1210.abstract N2 - SUMMARY: Hypoxic-ischemic injury is the most common cause of neonatal encephalopathy. T1-weighted punctate white matter lesions have been described in hypoxic-ischemic injury. We have reviewed a healthy volunteer neonatal population to assess the prevalence of punctate white matter lesions in neonates with no clinical signs of hypoxic-ischemic injury. Fifty-two subjects were scanned on a neonatal-specific 3T MR imaging scanner. Twelve patients were excluded due to the lack of T1-weighted imaging, leaving a total of 40 patients (35 term, 5 preterm) assessed in the study. One had a solitary T1-punctate white matter lesion. We concluded that solitary punctate white matter lesions have a low prevalence in healthy neonates.HIIhypoxic-ischemic injuryPWMLpunctate white matter lesionSDHsubdural hematoma ER -