RT Journal Article
SR Electronic
T1 White Matter Lesions Suggestive of Amyotrophic Lateral Sclerosis Attributed to Celiac Disease
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 880
OP 881
DO 10.3174/ajnr.A1826
VO 31
IS 5
A1 K.J. Brown
A1 V. Jewells
A1 H. Herfarth
A1 M. Castillo
YR 2010
UL http://www.ajnr.org/content/31/5/880.abstract
AB SUMMARY: CD is an autoimmune-mediated disorder of the gastrointestinal tract. Initial symptom presentation is variable and can include neurologic manifestations that may comprise ataxia, neuropathy, dizziness, epilepsy, and cortical calcifications rather than gastrointestinal-hindering diagnosis and management. We present a case of a young man with progressive neurologic symptoms and brain MR imaging findings worrisome for ALS. During the diagnostic work-up, endomysium antibodies were discovered, and CD was confirmed by upper gastrointestinal endoscopy with duodenal biopsies. MR imaging findings suggestive of ALS improved after gluten-free diet institution. ALSamyotrophic lateral sclerosisCDceliac diseaseFLAIRfluid-attenuated inversion recoveryIgAimmunoglobulin A