RT Journal Article SR Electronic T1 Utility of Dual-Energy CT to Improve Diagnosis of CSF Leaks on CT Myelography following Lateral Decubitus Digital Subtraction Myelography with Negative Findings JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology DO 10.3174/ajnr.A7628 A1 S.J. Huls A1 D.P. Shlapak A1 D.K. Kim A1 S. Leng A1 C.M. Carr YR 2022 UL http://www.ajnr.org/content/early/2022/09/08/ajnr.A7628.abstract AB SUMMARY: CSF leaks, including CSF-venous fistulas, which cause spontaneous intracranial hypotension, remain difficult to diagnose, even on digital subtraction myelography and CT myelography. Dual-energy CT technology has been used to improve diagnostic utility within multiple organ systems. The capability of dual-energy CT to create virtual monoenergetic images can be leveraged to increase conspicuity of contrast in CSF-venous fistulas and direct epidural CSF leakage to improve the diagnostic utility of CT myelography. Six cases (in 5 patients) are shown in which virtual monoenergetic images demonstrate a leak location that was either occult or poorly visible on high- or low-kilovolt series. This clinical report describes the novel application of dual-energy CT for the detection of subtle CSF leaks including CSF-venous fistulas.CTDIvolvolume CT dose indexCTMCT myelographyCVFCSF-venous fistulaDECTdual-energy CTDSMdigital subtraction myelographyLDDSMlateral decubitus digital subtraction myelographySIHspontaneous intracranial hypotensionVMIvirtual monoenergetic images