Convergent and Discriminant Validity in 28 Patients with AD and 28 Control Subjects in MR Group
| Atrophy Measures | Pearson’s r (95% CI), rWTH | |||
|---|---|---|---|---|
| Right | Left | Largest | ||
| Linear measures on coronal images | HL | |||
| Temporal horn | 0.73 (0.58–0.83) | 0.74 (0.59–0.84) | 0.83 (0.73–0.90) | |
| Width | CL | 0.78 (0.65–0.87) | 0.59 (0.39–0.74) | |
| Choroid fissure | HL | 0.47 (0.24–0.65) | 0.58 (0.37–0.73) | 0.53 (0.31–0.70) |
| Width | CL | 0.46 (0.22–0.64) | 0.41 (0.16–0.61) | |
| Hippocampal | HL | −0.57 (−0.72–−0.36) | −0.46 (−0.64–−0.22) | −0.47 (−0.65–−0.24) |
| Height | CL | −0.48 (−0.66–−0.25) | −0.48 (−0.66–−0.25) | |
| Interuncal distance | 0.44 (0.20–0.63) | 0.43 (0.19–0.62) | 0.40 (0.15–0.60) | |
| Interhemispheric fissure width | 0.16 (−0.11–0.41) | 0.07 (−0.20–0.33) | 0.15 (−0.12–0.40) | |
| Semiautomated volumetric measures | ||||
| Temporal horn | HL | 0.79 (0.67–0.87) | 0.77 (0.64–0.86) | 0.80 (0.68–0.88) |
| CL | 0.79 (0.67–0.87) | 0.58 (0.37–0.73) | ||
| Temporal lobe | HL | −0.62 (−0.76–0.43) | −0.60 (−0.75–−0.40) | −0.68 (0.51–0.80) |
| CL | −0.65 (−0.78–−0.47) | −0.50 (−0.67–−0.27) | ||
| Frontal lobe | HL | −0.50 (−0.67–−0.27) | −0.44 (−0.63–−0.20) | −0.49 (0.26–0.67) |
| CL | −0.54 (−0.70–−0.32) | −0.40 (−0.60–−0.15) | ||
| Manually traced volumetric measures | ||||
| Hippocampus | HL | −0.69 (−0.81–−0.52) | −0.66 (−0.79–−0.48) | −0.74 (−0.84–−0.59) |
| CL | −0.69 (−0.81–−0.52) | −0.59 (−0.74–−0.39) | ||
| Entorhinal cortex | HL | −0.56 (−0.72–−0.35) | −0.50 (−0.67–−0.27) | −0.58 (−0.73–−0.37) |
| CL | −0.50 (−0.67–−0.27) | −0.52 (−0.69–−0.30) | ||
Note.—HL indicates homolateral; CL, contralateral.