Findings observed on MR images
| Finding | Children with Mitochondrial Dysfunction (n = 22) | Children without Mitochondrial Dysfunction (n = 27) | Total (n = 49) |
|---|---|---|---|
| Normal | 6 | 19 | 25 |
| Abnormal | 16 | 8 | 24 |
| White matter | |||
| Necrosis | 3 | 0 | 3 |
| Diffuse | 9 | 4 | 13 |
| Posterior | 4 | 1 | 5 |
| Brainstem | 9 | 5 | 14 |
| Basal ganglia | 4 | 0 | 4 |
| Supratentorial atrophy | 8 | 2 | 10 |
| Other* | 1 | 2 | 3 |
* Vermian atrophy, n = 1; hyperintensity in one cerebellar hemisphere, n = 1; and hyperintensity in both cerebellar hemispheres, n = 1.