MR spectroscopic experiments

Animal	Infected with SIV	Sacrificed for Acute Ex Vivo Study	Published in In Vivo Study^*	Day of In Vivo MR Spectroscopy (dpi)	Day Sacrificed (dpi)
1	No	Yes	No	0	NA^†
2	No	Yes	No	0	NA^†
3	No	Yes	No	0	NA^†
4	No	Yes	No	0	NA^†
5	Yes	Yes	No	0, 11	12
6	Yes	Yes	No	0, 11	12
7	Yes	Yes	No	0, 11	12
8	Yes	Yes	Yes	0, 13	14
9	Yes	Yes	Yes	0, 13	14
10	Yes	Yes	Yes	0, 13	14
11	Yes	No	Yes	0, 13	293
12	Yes	No	Yes	0, 13	523
13	Yes	No	Yes	0, 11, 25	62
14	Yes	No	Yes	0, 11, 25	103
15	Yes	No	Yes	0, 11, 25	105
16	Yes	No	Yes	0, 11, 25	153
17	Yes	No	Yes	0, 11, 25	726
18	Yes	Yes	Yes	0, 13, 27	28
19	Yes	No	Yes	0, 13, 27	176
20	Yes	No	Yes	0, 13, 27	735
21	Yes	No	Yes	0, 13, 27	735
22	Yes	No	Yes	0, 13, 27	742

* For details on metabolic changes in the brain during acute SIV infection, see reference 1.
† NA = not applicable. Macaques 1–4 were used as controls.