Coagulation state and blood pressures at toxicity in 150 patients with PRES: 23 with hemorrhage, 127 without hemorrhage
| Blood Pressure at Toxicity | No. Pts | Normal Coagulation Platelets, Coagulation Parameters, and No Medications (No. Pts with PRES) | Abnormal Coagulation | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Intrinsic Coagulopathy Thrombocytopenia or Abnormal PT, PTT, INR (No. Pts with PRES) | Subtherapeutic, on Medications Affecting Platelet Function or Coagulation (No. Pts with PRES) | Therapeutic, on Medication Affecting Platelet Function or Coagulation (No. Pts with PRES) | |||||||
| W/O Hem | With Hem | W/O Hem | With Hem | W/O Hem | With Hem | W/O Hem | With Hem | ||
| Normotensive (MAP ≤ 105) | 44 | 15 | 3 | 17 | 1 | 3 | 1 | 2 | 2 |
| Mild HTN (MAP, 106–115) | 20 | 8 | 2 | 5 | 1 | 3 | 0 | 0 | 1 |
| Severe HTN (MAP ≥ 116) | 86 | 45 | 5 | 15 | 6 | 10 | 0 | 4 | 1 |
| Total | 150 | 68 | 10 | 37 | 8 | 16 | 1 | 6 | 4 |
Note:—W/O indicates without; Hem, hemorrhage; PT, prothrombin time; PTT, partial thromboplastin time; INR, international normalized ratio.