Validation of the methods for measuring brain volume performed in five volunteers
| Structure | Volume (mL) Measured by 5-mm Thick Sections | Volume (mL) Measured by 3-mm Thin Sections |
|---|---|---|
| White matter | 33.86 ± 3.33 | 34.00 ± 3.02 |
| Gray matter | 58.28 ± 3.77 | 58.44 ± 3.60 |
| CSF | 9.68 ± 3.26 | 9.54 ± 3.18 |
Note.—Data are mean ± SD. The mean difference between the two methods was 0.053 mL. A paired t test comparing 15 measurements made on thick sections to the same measurements made on thin sections was not significant (t statistic = 0.5524 with 14 degrees of freedom; P = .589).