Mean metabolite ratios
| MRSI Ratio | Control (n = 9) | TBI (n = 40) | Normal-Appearing Brain (n = 40) | Visible Hemorrhage (n = 33) | P Value* |
|---|---|---|---|---|---|
| NAA/Cr | 1.86 ± 0.11 | 1.50 ± 0.29† | 1.55 ± 0.52‡ | 1.33 ± 0.56† | .46 |
| NAA/Cho | 2.10 ± 0.19 | 1.44 ± 0.34† | 1.52 ± 0.58† | 1.16 ± 0.50† | .001† |
| Cho/Cr | 0.93 ± 0.07 | 1.12 ± 0.13† | 1.10 ± 0.39‡ | 1.24 ± 0.51† | .00† |
Note.—Ratios are average of mean ratios from each patient. Seven patients did not have voxels containing hemorrhage in the brain section sampled with MRSI.
* Normal versus hemorrhage.
† P ≤ .001 compared with controls, one-way ANOVA and post-hoc Bonferroni test.
‡ P ≤ 0.05 level compared to controls, one-way ANOVA and post-hoc Bonferroni test.