Clinical presentation and pathologic and DWI findings in patients with fungal cerebral infection or pyogenic bacterial abscess

PatientClinical PresentationLesion AspirationOrganismMR Imaging FindingADC (×10−3 mm2/s)ADC Ratio
LesionWM
1AcuteNot done, autopsyRhizopusMinimal enhancement, DWI heterogeneously hyperintense0.20 ± 0.050.86 ± 0.060.23
2AcuteNot done, autopsyAspergillusNo enhancement, DWI heterogeneously hyperintense0.23 ± 0.040.85 ± 0.050.27
3SubacuteNot done, autopsyAspergillusRing-enhancement, DWI peripherally hyperintense0.13 ± 0.070.69 ± 0.050.19
4SubacuteMucoid fluidAspergillusRing-enhancement, DWI centrally hyperintense0.59 ± 0.050.80 ± 0.060.74
5SubacuteNot done, autopsyAspergillusRing-enhancement, DWI centrally hyperintense0.71 ± 0.030.87 ± 0.040.81
6SubacuteMucoid fluidAspergillusRing-enhancement, DWI centrally hyperintense0.39 ± 0.080.74 ± 0.050.53
7SubacuteMucoid fluidScedosporiumRing-enhancement, DWI centrally hyperintense0.22 ± 0.050.58 ± 0.060.39
8SubacuteMucoid fluidAspergillusRing-enhancement, DWI hyperintense0.21 ± 0.080.66 ± 0.060.31
  • Note.—Mean lesion and white matter ADC and ADC ratio were, respectively, 0.33 ± 0.06 × 10−3 mm2/s, 0.76 ± 0.05 × 10−3 mm2/s, and 0.43 in the fungal group and 0.46 ± 0.06 × 10−3 mm2/s (difference not significant), 0.76 ± 0.05 × 10−3 mm2/s, and 0.61 (difference not significant) in the bacterial group.