Comparison of automated and manual AIF parameters

SubjectΔA0 (sec−1)ΔA1 (sec)ΔA2 (sec)d (mm)Correlation r*
TmaxCBF
121.520.690.3411.30.910.94
217.091.32−0.1715.90.870.92
30000.91.001.00
419.75−0.59−0.377.10.820.66
547.48−2.98−1.2311.40.700.60
611.390.32−0.8832.20.820.72
729.06−0.39−1.2818.90.680.74
837.220.57−0.6818.20.760.83
912.830.120.766.00.750.72
1032.611.30−0.3918.20.810.87
1125.22−0.79−0.1730.60.870.86
12−4.32−2.65−2.1535.90.810.82
131.24−0.24−0.3037.80.730.82
1427.30−2.46−0.2424.00.740.60
1515.26−0.19−0.073.00.850.88
1617.830.361.362.70.800.77
172.71−5.25−2.1835.00.540.68
180001.31.001.00
1919.27−0.62−0.0916.90.870.87
2011.780.71−0.8744.50.820.89
2110.17−0.19−0.3011.60.850.87
220001.31.001.00
Mean16.16−0.50−0.4117.50.820.82
SD13.49NANA13.450.110.12
P value<0.0010.3740.018NANANA
  • Note.—Differences were computed as the automated AIF parameter − manual AIF parameter. A0 = curve height (maximum concentration of contrast agent), A1 = curve center (time to peak), A2 = curve width, d = distance between automated and manual AIF pixels, NA = not applicable.

  • * Between automated and manual maps.