TABLE 2:

Changes in basilar artery diameter

Treatment groupsBaseline (mm)Vasospasm (mm)Treatment (mm)
ia nimodipine0.70 ± 0.030.40 ± 0.06*0.62 ± 0.02§
it nimodipine0.83 ± 0.030.42 ± 0.06*0.51 ± 0.06
ia vehicle0.67 ± 0.020.48 ± 0.01*0.48 ± 0.01
it vehicle0.59 ± 0.010.47 ± 0.01*0.41 ± 0.05
ia papaverine0.60 ± 0.020.43 ± 0.03*0.49 ± 0.03
  • All values were derived from n=5 experiments except for IT vehicle group where n=2 experiments were applied. Data were expressed as mean ± SEM.

  • * Statistically significant from baseline values (P < .05).

  • Statistically significant from values obtained during vasospasm (P < .05).

  • § Statistically significant from values obtained in either IT nimodipine or IA papaverine treatments.