TABLE 1:

Changes in vertebral artery diameter

Treatment groupsBaseline (mm)Vasospasm (mm)Treatment (mm)
ia nimodipine0.63 ± 0.040.41 ± 0.03*0.61 ± 0.03§
it nimodipine0.69 ± 0.040.40 ± 0.08*0.55 ± 0.55
ia vehicle0.55 ± 0.030.38 ± 0.02*0.39 ± 0.02
it vehicle0.52 ± 0.040.40 ± 0.05*0.36 ± 0.07
ia papaverine0.51 ± 0.020.35 ± 0.01*0.44 ± 0.03
  • All values were derived from n=5 experiments except for IT vehicle group, where n=2 experiments were applied.

  • * Statistically significant from baseline values (P < .05).

  • Statistically significant from values obtained at vasospasm (P < .05).

  • § Statistically significant from values obtained in IA papaverine treatment.