Summary of serial changes in leptomeningeal and CSF enhancement on postcontrast MR images
| Patient No./Age (y)/Sex | FAP type | Immediately after CE | 3 h after CE | 6 h after CE | 24 h after CE | ||||
|---|---|---|---|---|---|---|---|---|---|
| T1WI | FLAIR | T1WI | FLAIR | T1WI | FLAIR | T1WI | FLAIR | ||
| 1/46/F | Tyr114Cys | ± | + | ++ | ++ | + | ++ | − | + |
| 2*/40/M | Tyr114Cys | ± | + | ++ | ++ | + | ++ | − | + |
| 3*/52/F | Tyr114Cys | ± | + | ++ | ++ | + | ++ | − | + |
| 4/31/M | Val30Met | − | − | − | − | − | − | − | − |
| 5/40/F | Val30Met | − | − | − | − | − | − | − | − |
| 6/29/F | Val30Met | − | − | − | − | − | − | − | − |
Note.—FAP indicates familial amyloid polineuropathy
* liver transplantation; CE, contrast enhancement; T1WI, T1-weighted imaging; FLAIR, fluid-attenuated inversion recovery imaging; ++, marked enhancement; +, mild enhancement; ±, equivocal enhancement; −, no enhancement.