Comparison of baseline characteristics for patients with near occlusion (% of group)

Patient CharacteristicNASCET ITT (N = 137)ECST ITT (N = 125)P ValueMedical ITT (N = 114)Medical On- Treatment* (N = 78)
Assigned to carotid endarterectomy51.162.4
Age ≥65 y53.336.80.00748.244.9
Male sex79.682.40.5678.182.1
Hemispheric TIA or stroke in the past 180 d67.172.00.3974.682.0
Last ischemic event to randomization >4 wk43.160.00.00654.455.1
History of:
    Treated hypertension46.743.20.5745.644.9
    Diabetes mellitus16.89.60.0918.419.2
    Myocardial infarction or angina32.119.20.0228.924.4
    Intermittent claudication12.418.40.1814.915.4
    Smoking in the past year48.264.80.00755.353.8
Irregular/ulcerated carotid artery plaque§38.773.6<0.00155.359.0
  • Note.—ITT indicates intention-to-treat; TIA, transient ischemic attack.

  • * Medically treated patients who remained on medical therapy for the duration of the trial. There were no statistically significant different patient characteristics in comparison to the Medical ITT.

  • Mean age of patients: NASCET ITT, 64.0 years; ECST ITT, 61.4 years; P value = .01. Mean age of patients: Medical ITT, 63.3 years; Medical On-Treatment, 63.6 years.

  • Hemispheric, not ocular only events.

  • § Ipsilateral to the territory of the last ischemic event.