TABLE 2:

FA and ADC measurements in all four locations in HIV-positive patients and controls according to the viral load in plasma

Controls(n = 16)HIV+ Patients: Viral Load (Copies/mL)
<50 (n = 12)P Value50–100 000 (n = 19)P Value>100 000 (n = 22)P Value
Splenium FA753 ± 56770 ± 92791 ± 80755 ± 63NS
Genu FA717 ± 68680 ± 54679 ± 68679 ± 93NS
White matter FA404 ± 52367 ± 35381 ± 39402 ± 50NS
Hippocampus FA366 ± 65364 ± 101350 ± 54357 ± 46NS
Splenium ADC858 ± 114942 ± 155.023836 ± 96NS858 ± 72NS
Genu ADC1054 ± 1461286 ± 255NS1135 ± 192NS1159 ± 208NS
White matter ADC792 ± 44851 ± 70.028807 ± 42NS796 ± 57NS
Hippocampus ADC968 ± 1291081 ± 189NS1018 ± 123NS1029 ± 122NS
  • Note.—FA indicates fractional anisotropy; ADC, apparent diffusion coefficient (mm/s2); NS, not significant.