Parameter | Cutoff rCBVP Values | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
For Grading* | For Differentiation† | |||||||||
1.9a | 1.5b | 1.1c | 1.2d | 1.1e | 1.2f | 1.1g | 1.2h | 1.1i | 1.1j | |
ROC area | 0.841 | 0.879 | 0.747 | 0.955 | 0.733 | 0.933 | 0.900 | 0.909 | 0.914 | 0.905 |
SE | 0.063 | 0.067 | 0.070 | 0.037 | 0.079 | 0.053 | 0.066 | 0.071 | 0.069 | 0.061 |
AS | 0.000 | 0.000 | 0.004 | 0.000 | 0.012 | 0.000 | 0.000 | 0.000 | 0.001 | 0.000 |
Sensitivity | 68.18 | 80.00 | 61.11 | 90.91 | 58.33 | 86.67 | 91.67 | 81.82 | 92.86 | 92.86 |
Specificity | 100 | 95.83 | 88.24 | 100 | 88.24 | 100 | 88.24 | 100 | 90.00 | 88.24 |
PPV | 100 | 92.31 | 91.67 | 100 | 87.50 | 100 | 84.62 | 100 | 92.86 | 86.67 |
NPV | 83.72 | 88.46 | 51.72 | 89.47 | 60.00 | 89.47 | 93.75 | 89.48 | 90.00 | 93.75 |
Accuracy | 87.93 | 89.74 | 69.81 | 94.87 | 70.73 | 93.75 | 89.66 | 92.86 | 91.67 | 90.32 |
Note.—rCBVP indicates peritumoral relative cerebral blood volume; ROC, area under curve; SE, standard error; AS, asymptotic significance; PPV, positive predictive value; NPV, negative predictive value.
* Superscripts indicate:
a Low- and high-grade glial tumors;
b low- and high-grade astrocytic gliomas.
† Superscripts indicate:
c Low-grade glial tumors from metastases;
d high-grade glial tumors from metastases;
e low-grade astrocytomas from metastases;
f high-grade astrocytomas from metastases;
g low-grade non-astrocytic glial tumors from metastases;
h glioblastoma multiforme from metastases;
i diffuse astrocytomas from pilocytic astrocytomas;
j diffuse astrocytomas from metastases.