TABLE 5:

Statistically significant lowest cutoff rCBVP values tested for different mean differences

ParameterCutoff rCBVP Values
For Grading*For Differentiation
1.9a1.5b1.1c1.2d1.1e1.2f1.1g1.2h1.1i1.1j
ROC area0.8410.8790.7470.9550.7330.9330.9000.9090.9140.905
SE0.0630.0670.0700.0370.0790.0530.0660.0710.0690.061
AS0.0000.0000.0040.0000.0120.0000.0000.0000.0010.000
Sensitivity68.1880.0061.1190.9158.3386.6791.6781.8292.8692.86
Specificity10095.8388.2410088.2410088.2410090.0088.24
PPV10092.3191.6710087.5010084.6210092.8686.67
NPV83.7288.4651.7289.4760.0089.4793.7589.4890.0093.75
Accuracy87.9389.7469.8194.8770.7393.7589.6692.8691.6790.32
  • Note.—rCBVP indicates peritumoral relative cerebral blood volume; ROC, area under curve; SE, standard error; AS, asymptotic significance; PPV, positive predictive value; NPV, negative predictive value.

  • * Superscripts indicate:

  • a Low- and high-grade glial tumors;

  • b low- and high-grade astrocytic gliomas.

  • Superscripts indicate:

  • c Low-grade glial tumors from metastases;

  • d high-grade glial tumors from metastases;

  • e low-grade astrocytomas from metastases;

  • f high-grade astrocytomas from metastases;

  • g low-grade non-astrocytic glial tumors from metastases;

  • h glioblastoma multiforme from metastases;

  • i diffuse astrocytomas from pilocytic astrocytomas;

  • j diffuse astrocytomas from metastases.