TABLE 3:

Pearson correlation coefficients between imaging and clinical parameters

	Disease Duration		CS Duration		CS Dose (Daily)		CS Dose (Lifetime)
	Corr.	P Value	Corr.	P Value	Corr.	P Value	Corr.	P Value
CSF %	0.129	.522	0.087	.777	−0.269	.374	0.013	.966
Lesion %	0.024	.906	−0.303	.314	0.132	.668	−0.285	.345
MTR PH	−0.198	.322	0.136	.657	0.199	.515	0.201	.510
MTR mean	0.043	.831	0.135	.660	0.081	.793	0.171	.577
ADC PH	−0.015	.940	0.440	.133	0.508	.076	0.503	.080
ADC mean	0.170	.397	−0.138	.654	−0.099	.747	−0.183	.550
NAA/Cre	0.122	.571	0.408	.188	0.125	.699	0.405	.192
Cho/Cre	0.326	.119	0.511	.089	0.194	.547	0.493	.103

Note.—CS indicates corticosteroids; Corr., Pearson correlation coefficient; CSF %, cerebrospinal fluid volume as a fraction of intracranial volume; Lesion %, lesion volume as a fraction of brain parenchyma volume; MTR PH and MTR mean, magnetization transfer ratio histogram peak height (arbitrary unit) and mean (percent unit); ADC PH and ADC mean, apparent diffusion coefficient histogram peak height (arbitrary unit) and mean (10⁻⁶ s/mm²); NAA/Cre and Cho/Cre, ratio of N-acetylaspartate and choline to creatine.