Neuropsychologic findings in patients with ALS and healthy subjects
| Test | Healthy Subjects (9) | ALS Patients (16) | P |
|---|---|---|---|
| Age (years) | 51.8 (12.7) | 58.6 (10.2) | NS |
| Education (years) | 10.0 (4.6) | 8.7 (3.1) | NS |
| MMSE (cs) | 28.2 (1.6) | 26.6 (2.9) | NS |
| SPMT (z) | −0.5 (0.6) | −0.6 (0.5) | NS |
| BPIT 10 (z) | −0.1 (1.3) | 0.0 (0.9) | NS |
| BPIT 30 (z) | −0.1 (0.9) | −0.1 (1.1) | NS |
| FAS (z) | −0.4 (0.8) | −0.6 (1.3) | NS |
| Stroop | |||
| Word (z) | −0.5 (1.2) | −2.8 (4.1) | NS |
| Color (z) | −1.6 (2.5) | −4.4 (3.8) | NS |
| Interference (z) | −0.7 (1.6) | −1.9 (2.4) | NS |
| SDMT (z) | −1.4 (0.9) | −2.3 (1.1) | .025 |
Note:—Data are presented as mean (SD). P values were determined with the use of the Mann Whitney U test. ALS indicates amyotrophic lateral sclerosis; cs, corrected score; Z, Z-score; NS, not significant; MMSE, Mini Mental State Examination; SPMT, Spinnler Prose Memory Test; BPIT 10, Brown-Peterson Interference Test at 10 seconds; BPIT 30, Brown-Peterson Interference Test at 30 seconds; FAS, Verbal Fluency Test; Stroop, Stroop Color/Word Interference Test; SDMT, Symbol Digit Modalities Test.