Table 2:

rCBVT histogram metrics compared with rCBVmax and glioma grade, with correlation factors (r values) and Bonferroni-corrected significance <.005 (P values)

rCBVmaxGrade
r valueP valuer valueP value
Median0.68880<.00010.65849<.0001
Mean0.69444<.00010.67710<.0001
SD0.66036<.00010.71758<.0001
Mean500.68600<.00010.68166
SD500.53042<.00010.68441<.0001
Mean250.66355<.00010.68254<.0001
SD250.53365<.00010.66394<.0001
Mean100.63072<.00010.66342<.0001
SD100.57135<.00010.67416<.0001
Skew−0.42895<.0001−0.26876.0096
Kurt−0.29511.0043−0.34505.0008
PH−0.11601.2708−0.21640.0383
PP0.63647<.00010.62906<.0001
A1SD−0.22241.0331−0.23301.0254
  • Note:—rCBV indicates relative cerebral blood volume; mean50, mean of the top 50% of the histogram; SD50, SD of the top 50%; mean25, mean of the top 25%; SD25, SD of the top 25%; mean10, mean of the top 10%; SD10, SD of the top 10%; skew, skewness; kurt, kurtosis; PH, peak height of the histogram; PP, peak position (ie, the mode); and A1SD, area under the histogram curve within 1 SD. The highest correlations in each category are underlined; the metrics achieving significance are in bold.