Table 2:

The 96 genes that had a statistically significant (P < .05) differential expression between the aneurysm and the control artery

1Fast skeletal muscle troponin C mRNA
2Haptoglobin mRNA+
3Endothelial differentiation gene 1 protein+
4Muscle α-actinin subunit, N′-terminal region
5Matrix metalloproteinase 9+
7Alcohol dehydrogenase, class I+
9Myosin light chain 2
11Type VIII collagen α -1 chain
13Neutrophil attractant/activation protein-1 (NAP-1)
14Interleukin 1 receptor antagonist+
15Apolipoprotein E+
16IL-8 receptor
17Cytochrome P4B1 isoform
18Monocyte chemoattractant protein-1 (MCP-1)+
19Tissue inhibitor of metalloproteinase-4 (TIMP-4)+
20Myosin heavy chain (MHC)
21Transforming growth factor-β 2
22Heme oxygenase 1 (HO1)+
23Al adenosine receptor+
25p53 protein
26Peroxisome proliferator activated receptor (PPAR) gamma 3+
27Cathepsin L+
28Apolipoprotein B
29Elongation factor 1 β+
30Calmodulin-dependent protein kinase II-delta dash
31Secreted frizzled-related protein 2+
32Glutathione S-transferase
33Vascular cell adhesion molecule (VCAM-1)+
34Endothelin converting enzyme (ECE1)
35Platelet-derived growth factor-β+
36Matrix metalloproteinase-12+
39Glycoprotein IIb (GPIIb)+
40Metallo-elastase, macrophage+
41Fertilin α subunit
42Growth response 1 zinc-finger transcription factor
43α2 type I collagen
44α3 type IV collagen+
45Apolipoprotein D+
46Endothelin B receptor
47Insulin-like growth factor 1 precursor (IGF-1)+
48Neuregulin 1 α isoform
49Protein phosphatase-1 catalytic subunit (EC 3.1.3.-)+
50Heme oxygenase-2
51Class II alcohol dehydrogenase, isozyme 1+
52Functional messenger ribonucleoprotein particle major protein p50
53factor XI
54Rho-associated-Ser/Thr kinase+
55Acyl CoA binding protein
56Protein kinase Cβ (PKC-β)+
57Bone morphogenetic protein 2 (BMP-2)
58Heat shock protein 47+
59Retinoic acid receptor RXR α mRNA+
60α 1 type X collagen+
61Coagulation factor VII
63Elongation factor 1 delta (Rabef1D)+
64fas antigen spliced variant
65glucose transporter type 4 (GLUT4)
66Cellular disintegrin ADAM 6e (ADAM 6e)
67Atrial natriuretic polypeptides+
68Matrix metalloproteinase-2+
69Major histocompatibility complex class II RLA-DR-α gene+
70Tissue inhibitor of metalloproteinase-2 (TIMP2)+
71Adenosine A3 receptor mRNA
72Bone morphogenetic protein 7
73Forkhead transcription factor L2 (FoxL2) gene
74Neuronal nitric oxide synthase NOS1+
75Tissue-type plasminogen activator mRNA+
76Endothelin receptor type A
77Phosphorylase kinase α subunit mRNA
79Thrombomodulin precursor (Thbd)
80Neutrophil-activating peptide 78 (ENA-78)
81Calcineurin A β
82α-1 type V collagen (COL5A1)
83Interferon γ
84NADPH-cytochrome P450 reductase
85Fibroblast growth factor
86Thrombospondin 2-like protein (THBS2)+
87Tryptophan hydroxylase
88Hyperoxia induced (H1) 1 gene encoding a TIMP+
89Inducible nitric oxide synthase (NOS2)
90Glycoprotein IIIa (GPIIIa)+
91Elongation factor 1 γ+
93Calmodulin-dependent protein kinase II-γ dash2
94Protein inhibitor of neuronal nitric oxide synthase+
95Vascular endothelial growth factor receptor 3+
  • Note:—The genes are ranked according to the degree of significance of the differential expression. + indicates that the gene was overexpressed in the aneurysm; −, the gene was underexpressed in the aneurysm.