The differentially expressed genes are grouped into their respective molecular pathways
| Proteolytic enzymes | Apoptosis of smooth muscle cells | ||
| α-1-Antitrypsin | + | Caveolin | − |
| Cathepsin L | + | Fas antigen spliced variant | − |
| Cellular disintegrin ADAM 6e | − | Fast skeletal muscle troponin C mRNA | − |
| Hyperoxia induced (HI) 1 gene encoding a TIMP | + | Galectin-3 | + |
| Matrix metalloproteinase-2 | + | Heat shock protein 47 | + |
| Matrix metalloproteinase-9 | + | Muscle α -actinin subunit, N′-terminal region | − |
| Matrix metalloproteinase-12 | + | Myosin heavy chain (MHC) | − |
| Metallo-elastase, macrophage | + | Myosin light chain 2 | − |
| Osteonectin = SPARC | + | PPAR γ 3 | + |
| Tissue inhibitor of metalloproteinase-2 (TIMP-2) | + | p53 protein | − |
| Tissue inhibitor of metalloproteinase-4 (TIMP-4) | + | Secreted frizzled-related protein 2 | + |
| Coagulation cascade | Inflammatory cell recruitment | ||
| Coagulation factor VII | − | Adhesion molecule VCAM-1 (VCAM-1) | + |
| Factor XI | − | Endothelial differentiation gene 1 protein | + |
| Glycoprotein IIb (GPIIb) | + | Interferon γ | − |
| Glycoprotein IIIa (GPIIIa) | + | Interleukin-1 receptor antagonist | + |
| Haptoglobin mRNA | + | Interleukin-2 | − |
| Heme oxygenase-1 (HO1) | + | Interleukin-8 receptor | − |
| Heme oxygenase-2 | − | MHC class II RLA-DR-α gene | + |
| Platelet-derived growth factor-β | + | Monocyte chemoattractant protein-1 (MCP-1) | + |
| Thrombomodulin precursor (inhibitor of coagulation) | − | Neutrophil-activating peptide 78 (ENA-78) | − |
| Thrombospondin 2-like protein (THBS2) | + | Neutrophil attractant/activation protein-1 (NAP-1) | − |
| Tissue-type plasminogen activator mRNA | + | ||
| ECM proteins | Oxidative stress | ||
| α-1 type V collagen (COL5A1) | − | A1 Adenosine receptor | + |
| α-1 type X collagen | + | A3 Adenosine receptor | − |
| α-2 type I collagen | − | Alcohol dehydrogenase, class I | + |
| α-3 type IV collagen | +* | Apolipoprotein B | − |
| Bone morphogenetic protein 2 (BMP-2) | − | Apolipoprotein E | + |
| Bone morphogenetic protein 7 (BMP-7) | − | Atrial natriuretic polypeptide | + |
| Decorin=proteoglycan | − | Class II alcohol dehydrogenase, isozyme 1 | + |
| Fibroblast growth factor | − | Clone pApoD-L) apolipoprotein D (apoD) | + |
| Insulin-like growth factor 1 precursor (IGF-1) | + | CYP4B1 isoform | − |
| Osteoglycin | − | Endothelin-1 | − |
| Osteopontin | + | Endothelin B receptor | − |
| Transforming growth factor-β 2 | − | Endothelin converting enzyme (ECE1) | − |
| Type VIII collagen α -1 chain | − | Endothelin receptor type A | − |
| Glutathione S-transferase | − | ||
| Inducible nitric oxide synthase (NOS2) | − | ||
| NADPH-cytochrome P450 reductase | − | ||
| Neuronal nitric oxide synthase NOS1 | + | ||
| Protein inhibitor of neuronal nitric oxide synthase | + | ||
| Vascular endothelial growth factor receptor 3 | + |
Note:—+ indicates that the gene was overexpressed in the aneurysm; −, the gene was underexpressed in the aneurysm.