Table 1:

Demographics of patients with mTBI and MR imaging findings suggestive of axonal injury (AI)

No.Age/SexInjuryElapsed Time*PBVPGMPWMWBNAA (mmol/L)MRI Findings
119/FMVA3.8 years93.356.037.410.7Normal
221/MAssault1.2 years91.858.533.213.1Punctate AI foci
322/MMVA1 year94.460.034.413.1Normal
425/MAssault2.4 months94.856.837.912.1Punctate AI foci
525/FMVA8 days92.057.334.714.6Normal
628/MAssault1.2 months90.158.231.911.5Normal
730/FAssault7 months92.856.536.314.8Normal
830/MMVA3 years78.045.132.912.5Old contusion, volume loss, AI foci
931/FFall1 day93.652.241.36.2Normal
1035/FBA3 days84.754.829.910.5Normal
1135/FMVA31.5 years86.155.330.810.4Old contusion, AI foci
1236/FAssault9 days89.750.239.513.2Normal
1337/MBA3 days89.659.230.415.0Normal
1439/MMVA6.3 months89.451.038.39.5Normal
1541/MOther2 days89.851.038.89.1Normal
1643/MMVA4.3 years91.653.637.911.9Normal
1747/MFall7.9 years83.048.534.49.6AI focus
1847/FMVA1.7 years90.351.339.09.2Normal
1949/FFall4.6 years79.649.630.014.0Normal
2057/MFall9 days91.857.434.46.1Right frontal hemorrhage
Avg ± SD35 ± 1089.3 ± 4.754.1 ± 4.135.2 ± 3.511.3 ± 2.6
  • Note:—mTBI indicates mild traumatic brain injury; PBV, percentage brain volume; PGM, percentage gray matter; PWM, percentage white matter; WBNAA, whole-brain N-acetylaspartate; MVA, motor vehicle crash; BA, bicycle accident. All patients had a GCS score of 15.

  • * Time from injury to examination.

  • Injury involving a power tool.