Metabolite ratios from 3D MR spectroscopy automated processing
| Neonate | Gray Matter | White Matter | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Basal Ganglia | Thalami | Calcarine Cortex | Optic Radiation | Corticospinal Tracts | Posterior White Matter | Frontal White Matter | ||||||||
| NAA/Cho | Lac/Cho | NAA/Cho | Lac/Cho | NAA/Cho | Lac/Cho | NAA/Cho | Lac/Cho | NAA/Cho | Lac/Cho | NAA/Cho | Lac/Cho | NAA/Cho | Lac/Cho | |
| 1 | 0.51 | 0.09 | 0.53 | 0.04 | 0.72 | 0.16 | 0.70 | 0.12 | NA | NA | 0.69 | 0.18 | 0.81 | 0.17 |
| 2 | 0.53 | 0.12 | 0.64 | 0.05 | 0.65 | 0.15 | 0.83 | 0.01 | 0.60 | 0.15 | 0.46 | 0.09 | NA | NA |
| 3 | 0.67 | 0.14 | 0.64 | 0.11 | 0.66 | 0.13 | 0.53 | 0.03 | 0.66 | 0.04 | 0.65 | 0.07 | NA | NA |
| 4 | 0.61 | 0.07 | 0.73 | 0.09 | 0.88 | 0.17 | 0.91 | 0.10 | NA | NA | 0.76 | 0.19 | 0.84 | 0.04 |
| 5 | 0.61 | 0.09 | 0.71 | 0.06 | 0.66 | 0.12 | 0.57 | 0.04 | 0.85 | 0.20 | 0.69 | 0.14 | 0.71 | 0.12 |
| 6 | 0.50 | 0.12 | 0.66 | 0.07 | 0.56 | 0.10 | 0.70 | 0.07 | NA | NA | 0.79 | 0.08 | 0.55 | 0.18 |
| 7 | 0.61 | NA | 0.79 | NA | 0.87 | NA | 0.83 | NA | 0.75 | NA | 0.93 | NA | 0.46 | NA |
| 8 | 0.58 | NA | 0.67 | NA | 0.64 | NA | 0.56 | NA | 0.73 | NA | NA | NA | NA | NA |
| 9 | 0.47 | 0.13 | 0.65 | 0.12 | 0.67 | 0.14 | 0.47 | 0.15 | 0.65 | 0.11 | 0.56 | 0.13 | 0.63 | 0.28 |
| 10 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 11 | 0.74 | 0.09 | 0.84 | 0.05 | 0.68 | 0.15 | 0.67 | 0.06 | 0.70 | 0.03 | 0.81 | 0.09 | 0.79 | 0.10 |
| 12 | 0.54 | 0.07 | 0.61 | 0.04 | 0.62 | 0.10 | 0.43 | 0.15 | NA | NA | 0.90 | 0.13 | NA | NA |
| 13 | 0.57 | 0.07 | 0.68 | 0.02 | 0.65 | 0.20 | 0.33 | 0.00 | 0.95 | 0.11 | 0.57 | 0.02 | 0.67 | 0.07 |
| 14 | 0.61 | 0.13 | 0.88 | 0.09 | 0.76 | 0.15 | 0.74 | 0.05 | NA | NA | 0.68 | 0.12 | NA | NA |
| 15 | 0.63 | 0.03 | 0.72 | 0.06 | 1.30 | NA | 1.25 | 0.38 | NA | NA | NA | NA | 0.88 | 0.07 |
| 16 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Mean | 0.58 | 0.10 | 0.69 | 0.07 | 0.69 | 0.14 | 0.63 | 0.07 | 0.73 | 0.10 | 0.70 | 0.11 | 0.68 | 0.14 |
| SD | 0.07 | 0.03 | 0.09 | 0.03 | 0.09 | 0.03 | 0.17 | 0.05 | 0.11 | 0.06 | 0.14 | 0.05 | 0.13 | 0.08 |
Note:—The mean and SD calculations do not include metabolite values for neonate #15 with mild developmental delay. NA indicates data not available; NAA, N-acetylaspartate; Lac, lactate; Cho, choline.