Patients and controls
| Controls (n = 18) | Alcoholics (n = 26) | Nonalcoholics (n = 19) | |
|---|---|---|---|
| (M/F) Sex | 8/10 | 18/8 | 14/5 |
| Age (±SD), y | 55.7 ± 13.8 | 54.3 ± 12.7 NS | 61.1 ± 12.4 NS |
| CFF (±SD), Hz | 41.3 ± 1.6 | 37.3 ± 5.0** | 36.6 ± 4.9** |
| Child-Pugh grading | |||
| A | 10 | 9 | |
| B | 11 | 5 | |
| C | 5 | 5 | |
| HE grading | |||
| HE 0 | 7 | 5 | |
| mHE | 8 | 3 | |
| HE 1 | 5 | 6 | |
| HE 2 | 6 | 5 |
Note:—Forty-five cirrhotics and 18 controls were enrolled. In 8 controls, 2 alcoholics, and one nonalcoholic patient magnetic resonance spectroscopy could not be performed. Values are reported as mean ± SD. HE indicates hepatic encephalopathy; mHE, minimal HE.
** Significantly different from controls P < .01 (Mann-Whitney U; NS indicates no significant difference.