Summary of results
| Clinical | Quantitative | Infusion* | |
|---|---|---|---|
| Cortical gray matter | |||
| CBV (mL/g) | 0.082 ± 0.019 | 0.042 ± 0.015 | 0.030 ± 0.006 |
| MTT (s) | 3.3 ± 1.0 | 3.6 ± 0.7 | |
| CBF (mL/100 g/min) | 158.2 ± 37.7 | 75.6 ± 30.3 | 52.3 ± 13.7 |
| Deep gray matter | |||
| CBV (mL/g) | 0.064 ± 0.016 | 0.038 ± 0.010 | 0.027 ± 0.003 |
| MTT (s) | 2.6 ± 0.7 | 2.9 ± 0.4 | |
| CBF (mL/100 g/min) | 157.7 ± 60.9 | 81.3 ± 29.8 | 57.3 ± 11.2 |
| White matter | |||
| CBV (mL/g) | 0.040 ± 0.012 | 0.025 ± 0.007 | 0.018 ± 0.003 |
| MTT (s) | 4.3 ± 1.6 | 4.9 ± 1.4 | |
| CBF (mL/100 g/min) | 59.7 ± 19.9 | 32.5 ± 9.8 | 23.9 ± 5.1 |
Note:—CBV indicates cerebral blood volume; MTT, mean transit time; CBF, cerebral blood flow. Values are subject means ± SD.
* Infusion CBF was calculated using MTT from the quantitative bolus.