Baseline characteristics of treated subjects
| Variable | Overall (N = 111) | IV tPA (N = 30) | No IV tPA (N = 81) | P Value |
|---|---|---|---|---|
| Age, y (mean ± SD) | 66.2 ± 17.0 | 65.4 ± 13.5 | 66.5 ± 18.2 | .772† |
| Female, % | 56.8% | 56.7% | 56.8% | >.99‡ |
| Baseline NIHSSS* (mean ± SD) | 19.0 ± 6.3 | 19.6 ± 4.3 | 18.8 ± 6.9 | .565† |
| Hours to device treatment, median (range) | 4.2 (1.3–17.3) | 3.6 (2.1–7.0) | 4.4 (1.3–17.3) | .072§ |
| Procedure length (h), median (range) | 1.6 (0.5–5.8) | 1.6 (0.6–3.3) | 1.7 (0.5–5.8) | .353§ |
| No. of passes (mean ± SD) | 2.8 ± 1.6 | 2.7 ± 1.7 | 2.8 ± 1.6 | .460§ |
| IV tPA, N (%) | 30 (27.0) | 30 (100) | 0 (0) | – |
| IA tPA postretriever, N (%) | 43 (38.7) | 13 (43.3) | 30 (37.0) | .661‡ |
| Vascular occlusion location, N (%) | .296¶ | |||
| ICA | 1 (0.9) | 1 (3.3) | 0 (0) | |
| ICA-T | 32 (28.8) | 10 (33.3) | 22 (27.2) | |
| MCA | 68 (61.3) | 18 (60.0) | 50 (62.0) | |
| Vertebral alone | 0 | 0 | 0 | |
| Vertebral + basilar, basilar | 9 (8.1) | 1 (3.3) | 8 (9.9) | |
| P1 | 1 (0.9) | 0 (0) | 1 (1.2) |
Note:—IV tPA indicates intravenous tissue-type plasminogen activator; NIHSSS, National Institutes of Health Stroke Scale score; IA, intraarterial; ICA, intracranial carotid artery; ICA-T, ICA terminal bifurcation; MCA, middle cerebral artery.
* One posterior circulation (distal basilar artery occlusion) patient was enrolled against protocol with a baseline NIHSS score of 4. No other patients had a baseline NIHSS score below the required protocol score of 8. Procedure length was the time from groin puncture to final angiogram.
† t Test.
‡ Fisher exact test.
§ Wilcoxon rank-sum test.
¶ Likelihood ratio χ2 test.