Mean blood flow velocities in major cerebral arteries obtained with imaging transcranial Doppler sonography (TCDI) versus nonimaging transcranial Doppler sonographic (TCD) velocities in children with sickle cell disease
| Artery (n) | I | II | III | Angle of Insonation±SD (degrees) | Difference between I and III (%) | Difference between II and III (%) |
|---|---|---|---|---|---|---|
| TCDI Angle-Corrected Velocity ± SD (cm/s) | TCDI Velocity ± SD (cm/s) | TCD Velocity ± SD (cm/s) | ||||
| ICA Right (37) | 112 ± 34 | 90 ± 14* | 117 ± 18 | 23 ± 23 | 4 | 23** |
| ICA Left (36) | 122 ± 36 | 98 ± 27* | 119 ± 23 | 27 ± 23 | 2 | 18** |
| MCA Right (36) | 128 ± 26 | 106 ± 22* | 130 ± 19 | 30 ± 16 | 2 | 18** |
| MCA Left (35) | 135 ± 32 | 111 ± 33* | 134 ± 26 | 32 ± 13 | <1 | 17** |
| ACA Right (35) | 103 ± 34 | 74 ± 24* | 105 ± 23 | 37 ± 20 | 2 | 30** |
| ACA Left (34) | 120 ± 38 | 88 ± 25* | 105 ± 31 | 49 ± 14 | 12* | 16** |
| PCA Right (34) | 105 ± 33 | 84 ± 27* | 95 ± 23 | 32 ± 16 | 10 | 12** |
| PCA Left (31) | 99 ± 33 | 82 ± 21* | 94 ± 20 | 25 ± 17 | 5 | 13** |
Note:—I indicates angle-corrected TCDI; II, TCDI with no correction for the angle; III, TCD; ICA, internal carotid artery; MCA, middle cerebral artery; ACA, anterior cerebral artery; PCA, posterior cerebral artery; n, number of compared pairs.
* P <.05 I vs III
** P <.05 II vs III.