Spin-spin relaxation times (T2; ms) of Lac, NAA, Cho, and brain water
| Metabolite | Control Group (n = 10) | Neonatal Encephalopathy Infants (n = 17) | P Values | |||
|---|---|---|---|---|---|---|
| Normal/Mild Outcome (n = 10) | Severe/Fatal Outcome (n = 7) | Control Versus Normal/Mild Outcome | Control Versus Severe/Fatal Outcome | Normal/Mild Outcome Versus Severe/Fatal Outcome | ||
| Lac | 221.8 (196.3–287.7) | 242.8 (226.1–300.5) | 380.5 (272.3–417.5) | .43 | .04* | .01* |
| NAA | 368.9 (68.1) | 383.6 (85.8) | 490.6 (155.1) | .68 | .04* | .09 |
| Cho | 383.6 (84.2) | 408.0 (114.8) | 433.2 (40.6) | .59 | .17 | .41 |
| Cr | 199.2 (192.4–225.3) | 234.6 (212.4–254.2) | 259.7 (29.6) | .10 | <.001* | .13 |
| Brain water | 164.9 (19.3) | 157.0 (20.4) | 144.9 (32.3) | .38 | .13 | .36 |
Note:—Lac indicates lactate; NAA, N-acetylaspartate; Cho, choline; Cr, creatine.
* Denotes statistically significant differences between the groups. Values are mean (SD) and median (interquartile range) as appropriate.