Table 1:

Metabolite peak-area ratios for Lac/Cr, Lac/NAA, Lac/Cho, NAA/Cr, NAA/Cho, and Cho/Cr

Metabolite Ratio	Control Group (n = 10)	Neonatal Encephalopathy Group (n = 17)		P Values
Metabolite Ratio	Control Group (n = 10)	Normal/Mild Outcome (n = 10)	Severe/Fatal Outcome (n = 7)	Control Versus Normal/Mild Outcome	Control Versus Severe/Fatal Outcome	Normal/Mild Outcome Versus Severe/Fatal Outcome
Lac/Cr	0.38 (0.10)	0.41 (0.13)	0.70 (0.45–2.65)	.61	.04^*	.06
Lac/NAA	0.24 (0.06)	0.29 (0.09)	0.54 (0.35–2.66)	.11	.02^*	.03^*
Lac/Cho	0.15 (0.03)	0.19 (0.05)	0.32 (0.22–1.26)	.06	.02^*	.04^*
NAA/Cr	1.59 (0.19)	1.41 (0.28)	1.16 (0.14)	.09	<.001^*	.04^*
NAA/Cho	0.66 (0.08)	0.67 (0.09)	0.56 (0.11)	.73	.04^*	.04^*
Cho/Cr	2.47 (0.57)	2.10 (0.31)	2.12 (0.36)	.09	.17	.91

Note:—Lac indicates lactate; NAA, N-acetylaspartate; Cho, choline; Cr, creatine.
* Denotes statistically significant differences between the groups. Values are mean (SD) and median (interquartile range) as appropriate.