Author | Age (y)/Sex | Vessel Treated (NASCET) | Other Territories | Vascular Risk Factors | Time from Last Symptom | Radiographic Pathologies before Treatment | Blood Pressure (mmHg) | Anticoagulation (Procedural) | Time between End of Procedure and Setup of Neurologic Event | Localization of ICH | HPS Suspect Prodro-mata | Clinical Out-come | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Embolic | Hemodynamic | Microangio-pathic | During Procedure | After Procedure | During Neurologic Event | Heparin | Others | ||||||||||
McCabe et al9 | 68/M | Left ICA (95%) | No data | Smoking, alcohol | 5 mo, incomplete remission | Cortical | None | Moderate periventricular | 160/90–175/105 | 140–160/95 | 150/85 | 5000 IU | ASA, dipyridamole | 7 h | Ipsilateral basal ganglia | None | Fatal |
Moriet al10 | 71/M | Left ICA (99%) | No data | Hypertension | None, recurrent TIAs | None | None | Yes | ≤142 systolic | No data | 170–190 systolic | 10 000 IU | Warfarin, ticlopidin | 4 h | Ipsilateral basal ganglia | None | Fatal |
Morrishet al6 | 87/M | Left ICA (95%) | No significant stenosis in contralateral ICA | No data | 4 mo | None | None | Subcortical | No data | 110/60 | 125/80 | 7000 IU | ASA, ticlopidin | 10 h | No data | None | Fatal |
Morrishet al6 | 62/F | Right ICA (95%) | No significant stenosis in contralateral ICA | No data | 6 wk | Large cortical | None | None | No data | 173/64 | 173/64 | 9000 IU | ASA, ticlopidin | 15 min | Ipsilateral basal ganglia | None | Fatal |
Chamorroet al11 | 43/M | Right ICA (95%) | No stenosis | Hypertension | 7 d | Acute embolic | None | Lacunar | 135/75–180/80 | 100/60–125/60 | 180/75 | 5000 IU | ASA, clopidogrel, urokinase | ∼6 h | Contralateral basal ganglia | None | Fatal |
Qureshiet al12 | 66/F | ICA (99%) | No data | Hypertension, smoking, hyperlipidemia | 2 d after ischemic stroke | None | None | Lacunar | No data | Max. 165 systolic | No data | ACT: 356 s | ASA, clopidogrel, abciximab | 1 h | Basal ganglia | None | Fatal |
Qureshiet al12 | 56/M | ICA (90%) | No data | Hypertension, coronary and peripheral artery disease | 4 d after TIA | None | None | None | No data | Max. 199 systolic | No data | ACT: 180 s | ASA, clopidogrel, abciximab | 8 h | Basal ganglia | None | Fatal |
Qureshiet al12 | 61/M | ICA (90%) | No data | Coronary and peripheral artery disease | 4 wk after ischemic stroke | Multiple small infarcts ipsilateral to stenosis | None | None | No data | Max. 187 systolic | No data | ACT: 320 s | ASA, clopidogrel, abciximab | 10 min | Lobar | None | Fatal |
Qureshiet al12 | 46/F | ICA (80%) | No data | Hypertension, smoking | 1 d after TIA | None | None | None | No data | Max. 260 systolic | No data | ACT: 273 s | ASA, clopidogrel, abciximab | 1 h | Lobar | None | Fatal |
Friedmanet al13 | 82/M | Right ICA (90%) | Left ICA (60%), no collateralization from anterior or posterior communicating arteries | Positive family history | Few days | None | Yes, restricted diffusion | None | ∼140 systolic | ∼140 systolic | No data | 5000 IU | ASA, clopidogrel | 45 min | Ipsilateral basal ganglia | None | Fatal |
Abou-Cheblet al14 | Not applicable | Left ICA (99%) | Right ICA (80%) | Hypertension | Not applicable | ∼5000 IU (ACT > 250 s) | ASA, clopidogrel | 1 h | Ipsilateral basal ganglia | None | Fatal | ||||||
Case reported | 65/F | Right ICA (95%) | Left ICA (80%), proximal VA stenosis bilateral | Hypertension, smoking, alcohol, positive family history | Maximum 14 d, incomplete remission | Cortical | Yes, restricted diffusion | Mild | 140/70 | 120/70 | Max. 160 systolic | 5000 IU (ACT: 278 s) | ASA, clopidogrel | 30 min | Ipsilateral basal ganglia | None | Fatal |
Note:—NASCET indicates North American Symptomatic Carotid Endarterectomy Trial; ICA, internal carotid artery; VA, vertebral artery; TIA, transient ischemic attack; ASA, acetyl salicylic acid; ACT, activated clotting time.