GM and WM mean MTR of the frontal, parietal, temporal, and occipital lobes
| Lobe | Tissue | Normal Cognition (n = 43) | MCI (n = 19) | AD (n = 55) |
|---|---|---|---|---|
| Frontal | GM | 27.1 (±1.9) | 26.0 (±2.0) | 25.5 (±1.9)a |
| WM | 35.0 (±1.0) | 34.5 (±1.3) | 34.4 (±1.1)a | |
| Parietal | GM | 26.9 (±2.0) | 26.2 (±1.7) | 25.7 (±1.9)a |
| WM | 34.8 (±1.0) | 34.6 (±1.3) | 34.3 (±1.3)a | |
| Temporal | GM | 29.7 (±1.4) | 28.9 (±1.3) | 27.6 (±1.5)a |
| WM | 34.7 (±1.1) | 34.5 (±1.2) | 34.2 (±0.9)a | |
| Occipital | GM | 28.8 (±1.9) | 29.1 (±1.5) | 27.9 (±1.9)a |
| WM | 33.8 (±0.9) | 33.8 (±1.1) | 33.4 (±1.1) |
Note:—Data are represented as mean (± SD).
a Differs from the group with normal cognition (P < .01).