Diffusion tensor measurements (median [ranges]) of selected NAWM regions among AD, MCI, and NC subjectsa
| AD (n = 6) | MCI (n = 11) | NC (n = 8) | |
|---|---|---|---|
| Frontal FA | 0.25 (0.22–0.29)b | 0.29 (0.25–0.38) | 0.33 (0.27–0.39) |
| Frontal DA | 1.13 (0.97–1.18) | 1.06 (0.95–1.13) | 1.07 (1.03–1.13) |
| Frontal DR | 0.78 (0.67–0.85)bc | 0.69 (0.60–0.75) | 0.64 (0.59–0.74) |
| Temporal FA | 0.38 (0.34–0.43)bc | 0.43 (0.40–0.48)b | 0.50 (0.45–0.58) |
| Temporal DA | 1.18 (1.16–1.24)b | 1.20 (1.15–1.36)b | 1.29 (1.27–1.36) |
| Temporal DR | 0.66 (0.61–0.71)b | 0.61 (0.55–0.70) | 0.57 (0.48–0.62) |
| Parietal FA | 0.38 (0.35–0.43)b | 0.40 (0.33–0.43)b | 0.46 (0.44–0.48) |
| Parietal DA | 1.14 (1.07–1.25) | 1.12 (1.05–1.18) | 1.15 (1.12–1.23) |
| Parietal DR | 0.63 (0.61–0.66)b | 0.60 (0.57–0.64)b | 0.57 (0.54–0.59) |
| Occipital FA | 0.42 (0.36–0.43) | 0.45 (0.39–0.56) | 0.45 (0.33–0.50) |
| Occipital DA | 1.19 (1.15–1.24) | 1.21 (1.06–1.42) | 1.19 (1.09–1.38) |
| Occipital DR | 0.62 (0.60–0.66) | 0.60 (0.52–0.68) | 0.59 (0.50–0.72) |
Note:—NC indicates control subjects.
a DA and DR are in units of 10−3 mm2/s.
b Statistically significant versus NC.
c Statistically significant versus MCI.