Table 1:

Characteristics of patients with Alzheimer disease (AD) (n = 21) and nondemented elderly control subjects (n = 15) including age, mini-mental state examination (MMSE), hippocampal sulcus (HS) width, number and size of hippocampal cavities (HC), and medial temporal lobe atrophy (MTA) score

Characteristic	Mean (SD)
Characteristic	AD Patients	Control Subjects	P Value
Age	69.3 (10.9)	68.9 (8.0)	.91
MMSE score^*	18.8^† (4.5)	27.9^† (1.9)	<.0001
HS width^‡ (mm), observer 1	2.9 (1.0)	1.4 (0.6)	<.0001
HS width^‡ (mm), observer 2	2.8 (1.1)	1.4 (0.7)	<.0001
HS width^‡ (mm), interobserver average	2.8 (0.9)	1.4 (0.6)	<.0001
Number of HC, observer 1	2.6 (3.2)	3.6 (2.8)	.32
Number of HC, observer 2	1.9 (2.4)	3.6 (2.9)	.06
Number of HC, interobserver average	2.2 (2.7)	3.6 (2.8)	.15
Mean size of HC (mm), observer 1	1.7 (1.0)	2.0 (1.1)	.29
Mean size of HC (mm), observer 2	1.3 (1.1)	2.0 (0.8)	.06
Mean size of HC (mm), interobserver average	1.5 (0.9)	2.0 (0.9)	.10
MTA score^‡^§, observer 1	2.2^† (1.0)	1.1^† (0.7)	<.01
MTA score^‡^§, observer 2	1.7^† (1.1)	0.6^† (0.7)	<.01
MTA score^‡^§, interobserver average	2.0^† (1.1)	0.8^† (0.6)	<.01

Note:—
* Lower values indicate greater severity.
† Please note that means of scores are presented, whereas we used the Mann-Whitney U test to compare differences between groups.
‡ Values are left/right averages.
§ Higher values indicate greater severity.