Demographic information and summary of imaging findings for 6 subjects with pAgCC
| Subject | Age (yr) | Sex | Structural Malformations* | Fractional Fragment Position | Predicted Homotopic Connections† | Observed Homotopic Connections‡ | Observed Heterotopic Connections‡§ |
|---|---|---|---|---|---|---|---|
| 1 | 11 | F | None | 0.32–0.45 | PF | AF, PF, OT | None |
| 2 | 48 | F | Right lateral periventricular nodular heterotopia | 0.09–0.44 | AF, PF | AF, PF, OT | None |
| 3 | 36 | M | Left frontal periventricular nodular heterotopia | 0.10–0.33 | AF, PF | AF | AF(L)-OT(R) |
| 4 | 37 | F | None | 0.46–0.70 | PF | PF, OT | PF(L)-OT(R) |
| 5 | 70 | M | None | 0.38–0.50 | PF | AF, OT | AF(L)-OT(R) |
| AF(R)-OT(L) | |||||||
| 6 | 37 | M | None | 0.20–0.83 | PF, PA | AF, PF, OT | AF(R)-OT(L) |
| AF(L)-OT(R) | |||||||
| AF(R)-PF(L) | |||||||
| PF(R)-OT(L) |
Note:—AF indicates anterior frontal; PF, posterior frontal; PA, parietal; OT, occipitotemporal; L, left; R, right; pAgCC, partial agenesis of the corpus callosum.
* Structural malformations and fragment position (as a fraction of normal callosal length) were determined from high-resolution T1-weighted structural images.
† Predicted homotopic connectivity is based on fragment position.
‡ Observed homotopic and heterotopic callosal connections are determined from QBI tractography.
§ For heterotopic connections, the hemisphere of each connected cortical region is also denoted in parentheses.