Cortical hamartoma perfusion imaging findings in a series of 13 patients evaluated with pulsed arterial spin-labeling

PtAge (yr)Seizures per WeekSeizure FrequencyNo. Cortical Hamartomas >1 cmNo. Hyperperfused HamartomasNo. Hypoperfused HamartomasNo. Normally Perfused HamartomasMean Normal GM Perfusion (mL/100 g/min)Mean Hyperperfused Lesions (mL/100 g/min)Mean Hypoperfused Lesions (mL/100 g/min)
1a0.70None12011163.826.5
1b12011167.926.3
2a70None100100116.663.8
2b9063123.079.8
3211 per week210210173.6104.6
4a822 per week, left facial twitch9351108.1155.168.1
4b9360112.4154.035.3
570None, last 8 months3120102.3127.786.7
62344 per week, EEG left temporal23121152.861.420.0
750None, last 3 months410410131.423.0
8333–4 per week181170163.2186.761.6
9120None last 10 years505085.425.6
1060None last 2 years221210122.2151.245.2
1130None last 3 months19018199.638.9
12100None last 3 months808084.622.8
131121–2 per week24024060.023.8
  • Note:—Pt indicates patient; EEG, electroencephalogram; GM, gray matter.