Sensitivity and specificity of SPACE and MPRAGE according to the observer groups*
| Residents | Neuroradiologists | |||
|---|---|---|---|---|
| SPACE | MPRAGE | SPACE | MPRAGE | |
| Sensitivity | 96.5† | 59.4 | 98.8‡ | 69.4 |
| (164/170) | (101/170) | (168/170) | (118/170) | |
| Specificity | 90 | 88.9 | 93.3 | 90.6 |
| (162/180) | (160/180) | (168/180) | (163/180) | |
| Accuracy | 93.1§ | 74.6 | 96.0¶ | 80.3 |
| (326/350) | (261/350) | (336/350) | (281/350) | |
| False-positive | 10 | 11.1 | 6.7 | 9.4 |
| (18/180) | (20/180) | (12/180) | (17/180) | |
| False-negative | 3.5‖ | 40.6 | 1.2# | 30.6 |
| (6/170) | (69/170) | (2/170) | (52/170) | |
Note:—SPACE indicates sampling perfection with application-optimized contrasts by using different flip angle evolutions; MPRAGE, magnetization-prepared rapid acquisition of gradient echo.
* Data are percentages; numbers in parentheses are raw data.
† P= .0002.
‡ P = .003.
§ P = .0008.
¶ P = .002.
‖ P = .0002.
# P = .01.