Characteristics | Patients aged <80 Years (N = 77) | Patients aged ≥80 Years (N = 24) | P value |
---|---|---|---|
Men | 42 (55%) | 13 (54%) | .97 |
Initial NIHSS score (mean ± SD) | 18.6 ± 7.5 | 20.1 ± 6.1 | .37 |
Initial NIHSS score strata | |||
<10 | 5 (6%) | 1 (4%) | .42 |
10–19 | 42 (55%) | 10 (42%) | |
≥20 | 30 (39%) | 14 (54%) | |
Symptom onset to treatment in hours (mean ± SD) | 4.3 ± 2.2 | 4.6 ± 1.6 | .53 |
Intravenous rtPA used | 16 (21%) | 3 (13%) | .36 |
Location of arterial occlusion | |||
Internal carotid artery | 23 (30%) | 11 (46%) | .31 |
Middle cerebral artery | 41 (53%) | 12 (50%) | |
Basilar artery | 11 (14%) | 1 (4%) | |
Others | 2 (3%) | 0 (0%) | |
Angiographic occlusion grade (Qureshi grade) | |||
Grades I–III | 40 (53%) | 12 (57%) | .76 |
Grades IV–V | 35 (47%) | 9 (43%) | |
Intra-arterial thrombolysis | |||
Pharmacologic only | 14 (18%) | 6 (25%) | .46 |
Pharmacologic and mechanical | 63 (82%) | 19 (75%) | |
Posttreatment recanalization | |||
No recanalization (TIMI 0–1) | 17 (22%) | 9 (38%) | .13 |
Partial or complete recanalization | 60 (78%) | 15 (62%) | |
Partial recanalization (TIMI 2) | 30 (39%) | 10 (42%) | |
Complete recanalization (TIMI 3) | 30 (39%) | 5 (20%) | |
NIHSS score at 24 hours (mean ± SD) | 16.6 ± 13 | 19.3 ± 12 | .34 |
Early neurologic improvement | 36 (47%) | 11 (46%) | .94 |
Asymptomatic ICH | 4 (5%) | 1 (4%) | .84 |
Symptomatic ICH | 7 (9%) | 2 (8%) | .91 |
mRS at 1–3 months | |||
mRS 0–2 | 29 (38%) | 5 (21%) | .13 |
mRS ≥3 | 48 (62%) | 19 (79%) | |
Mortality | 22 (29%) | 13 (54%) | .02 |
Note:—NIHSS indicates National Institutes of Health Stroke Scale; rtPA, recombinant tissue plasminogen activator; TIMI, Thrombolysis in Myocardial Infarction; mRS, modified Rankin scale; ICH, intracranial hemorrhage.