Changes in lesion volumes
| Reference | Year | Patients with Lesion Progression | Patients with No Change | Patients with Lesion Reversal |
|---|---|---|---|---|
| Delgado-Mederos et al30* | 2007 | 80% | 13% | 7% |
| Rivers et al29† | 2006 | 44% | n/a | 56% |
| Seitz et al28† | 2005 | 52% | n/a | 48% |
| Ritzl et al27 | 2004 | 8% | 8% | 83% |
| Schramm et al26 | 2004 | 69% | 0% | 31% |
| Schaefer et al25 | 2004 | 88% | 6% | 6% |
| Fiehler et al24‡ | 2004 | 79% | n/a | 21% |
| Shih et al23 | 2003 | 36% | 0% | 64% |
| Schramm et al22 | 2002 | 85% | 5% | 10% |
| Parsons et al21 | 2002 | 61% | 25% | 14% |
| Schellinger et al20§ | 2001 | 100% | n/a | 0% |
| Kidwell et al18 | 2000 | 29% | 0% | 71% |
| Parsons et al19 | 2000 | 42% | 26% | 32% |
| Beaulieu et al15 | 1999 | 47% | 20% | 33% |
| Neumann-Haefelin et al17 | 1999 | 50% | 10% | 40% |
| Sorensen et al16 | 1999 | 70% | 17% | 13% |
| Barber et al31 | 1998 | 44% | 13% | 44% |
| Tong et al14‖ | 1998 | 75% | 13% | 13% |
Note:—n/a indicates not applicable.
* Percentages based on author's report of stratified lesion volumes.
† Percentages based on author's dichotomization of DWI volume as more or less than follow-up T2 volume.
‡ Initial volumes determined by apparent diffusion coefficient decrease of >20%, not DWI hyperintensity.
§ Based on author commentary, not individual data points.
‖ Values inferred from data presented in graphic form.