Table 2:

Clinical manifestations of nonalcoholic WE

Early-Stage Manifestations
    Non-neurologic specific manifestations
        Fatigue, anorexia, dizziness, nausea, vomiting, weight loss, tachycardia
    Common neurological manifestations
        Learning and memory disturbance, confabulation
        Altered mental state: mental sluggishness, apathy, inattentiveness and inability to concentrate, spatial and personal disorientation, mild or marked confusion
        Ocular abnormalities: nystagmus, diplopia, upward gaze paresis, abducens palsy, conjugate gaze palsies
        Incoordination of gait and trunk ataxia
        Generalized hyporeflexia
        Disturbances of consciousness: drowsiness, lethargy, and mild coma
    Uncommon neurologic manifestations
        Stupor
        Dysarthria
        Hemiparesis, flaccid paraplegia, or quadriplegia
        Choreic dyskinesias
        Pupillary abnormalities: anisocoria, sluggish reactivity
        Optic neuropathy: amaurosis, visual disturbance, papilledema, retinal hemorrhage
        Epileptic seizures
        Hearing loss
        Hallucinations and behavioral disturbances
        Painful paresthesias: burning, prickling, or tingling
Late-Stage Manifestations
    Hypotension
    Hyperthermia or hypothermia
    Deep coma