Demographic and clinical characteristics of normal control subjects and multiple sclerosis patients, according to disease type
| Variable | NC (n= 19) | MS (n = 65) | CIS (n = 11) | RR (n = 34) | SP (n = 14) | PP (n = 7) |
|---|---|---|---|---|---|---|
| Female, n (%) | 10 (52.6) | 48 (72.7) | 9 (81.8) | 26 (76.5) | 9 (64.3) | 4 (57.1) |
| Age in years, mean (SD) | 30.4 (12) | 41.2 (12.4) | 36.9 (9.1) | 42.4 (8.6) | 47.2 (11.4) | 59.9 (12) |
| Disease duration in years, mean (SD) | NA | 11.8 (10.7) | 1.1 (1.4) | 11.1 (8.2) | 17.1 (9.9) | 19.6 (18.6) |
| EDSS, mean (SD) | NA | 3.1 (2.1) | 1.6 (0.3) | 2.1 (1.3) | 5.0 (1.8) | 5.8 (1.3) |
Note:—NC indicates normal control subjects; MS, multiple sclerosis; RR, relapsing-remitting; SP, secondary-progressive; PP, primary-progressive; CIS, clinically isolated syndrome; NA, not applicable.