DTI values per ROI*

ROI	Group	No.	Mean Value
ROI	Group	No.	ADC × 10⁻³ mm²/s	FA	λ₁ × 10⁻³ mm²/s	λ₂ × 10⁻³ mm²/s	λ₃ × 10⁻³ mm²/s	A_m
POWM	NAS	50	0.79 ± 0.05	0.31 ± 0.06	1.09 ± 0.06	0.74 ± 0.06	0.52 ± 0.07	0.20 ± 0.04
	Controls	8	0.75 ± 0.02	0.36 ± 0.06	1.06 ± 0.04	0.70 ± 0.05	0.48 ± 0.03	0.19 ± 0.06
FWM	NAS	50	0.80 ± 0.04	0.31 ± 0.04	1.04 ± 0.05	0.76 ± 0.04	0.56 ± 0.05	0.16 ± 0.02
	Controls	8	0.75 ± 0.03	0.30 ± 0.02	0.98 ± 0.04	0.71 ± 0.04	0.53 ± 0.04	0.16 ± 0.02
GP^†	UBO	23	0.83 ± 0.07	0.25 ± 0.06	1.02 ± 0.12	0.79 ± 0.07	0.64 ± 0.06	0.13 ± 0.04
	NAS	27	0.72 ± 0.04	0.17 ± 0.04	0.83 ± 0.05	0.70 ± 0.04	0.60 ± 0.04	0.09 ± 0.01
	Controls	8	0.70 ± 0.02	0.16 ± 0.02	0.81 ± 0.03	0.68 ± 0.03	0.58 ± 0.03	0.08 ± 0.02
TH	UBO	7	0.81 ± 0.04	0.29 ± 0.10	1.04 ± 0.05	0.75 ± 0.06	0.61 ± 0.08	0.15 ± 0.04
	NAS	43	0.76 ± 0.03	0.31 ± 0.05	1.02 ± 0.05	0.70 ± 0.04	0.55 ± 0.04	0.17 ± 0.03
	Controls	8	0.70 ± 0.02	0.36 ± 0.06	0.98 ± 0.07	0.63 ± 0.03	0.47 ± 0.02	0.21 ± 0.04
HI	UBO	23	0.90 ± 0.05	0.20 ± 0.04	1.07 ± 0.51	0.87 ± 0.42	0.72 ± 0.51	0.10 ± 0.03
	NAS	25	0.84 ± 0.04	0.21 ± 0.04	1.04 ± 0.07	0.82 ± 0.04	0.66 ± 0.04	0.12 ± 0.03
	Controls	8	0.80 ± 0.02	0.21 ± 0.02	0.97 ± 0.02	0.78 ± 0.03	0.63 ± 0.03	0.11 ± 0.02
CWM^†	UBO	25	0.85 ± 0.14	0.32 ± 0.11	1.11 ± 0.08	0.85 ± 0.35	0.61 ± 0.13	0.20 ± 0.18
	NAS	25	0.72 ± 0.06	0.43 ± 0.11	1.05 ± 0.13	0.65 ± 0.07	0.47 ± 0.09	0.23 ± 0.07
	Controls	8	0.68 ± 0.02	0.45 ± 0.08	1.00 ± 0.06	0.62 ± 0.05	0.43 ± 0.04	0.23 ± 0.05
CP	UBO	16	0.89 ± 0.05	0.44 ± 0.06	1.31 ± 0.09	0.77 ± 0.09	0.54 ± 0.09	0.25 ± 0.04
	NAS	33	0.81 ± 0.05	0.47 ± 0.05	1.32 ± 0.11	0.69 ± 0.09	0.47 ± 0.05	0.30 ± 0.05
	Controls	8	0.80 ± 0.05	0.51 ± 0.04	1.32 ± 0.12	0.63 ± 0.05	0.43 ± 0.04	0.33 ± 0.03

Note:—ROI indicates region of interest; NAS, normal-appearing sites; POWM, parieto-occipital white matter; FWM, frontal white matter; GP, globus pallidus; TH, thalamus; HI, hippocampus; CWM, cerebellar white matter; CP, cerebral peduncle; UBO, unidentified bright object; ADC, apparent diffusion coefficient; FA, fractional anisotropy; A_m, axial anisotropy.
* Values are averaged for left and right hemispheres. For all indices, mean values ± SD are given for regions with UBOs, regions without UBOs (NAS), and healthy controls.
† Nonparametric data.