Table 4:

VBM results of contrast between MCI converters and MCI nonconverters (no covariates)*

MNI MaxpClusterKTpFDRCluster %R/LLocation
−58 0 -150.00015240 (5.2 cm3)5.10.0446.51LeftSuperior temporal gyrus
40.88LeftMiddle temporal gyrus
6.16LeftSuperior temporal pole
5.23LeftMiddle temporal pole
−24 -4 -240.0023220 (3.2 cm3)4.70.0457.30LeftHippocampus
21.46LeftParahippocampal gyrus
10.09LeftFusiform gyrus
6.27LeftAmygdala
4.41LeftMiddle temporal pole
−52 -64 380.051524 (1.5 cm3)4.70.0467.78LeftAngular gyrus
29.27LeftInferior parietal lobule
2.95LeftSupramarginal gyrus
56 12 -170.041627 (1.6 cm3)4.50.0447.80RightMiddle temporal gyrus
22.54RightSuperior temporal pole
16.40RightInferior temporal gyrus
6.63RightSuperior temporal gyrus
5.12RightMiddle temporal pole
  • Note:—pCluster indicates p cluster corrected; K, cluster size; T, T value; pFDR, p false discovery rate; MCI, mild cognitive impairment; MNI, Montreal Neurologic Institute.

  • * Statistics calculated within a brain mask excluding the cerebellum. Thresholding was performed at P < .0001 (uncorrected) and subsequently only the cluster surviving corrected thresholds reported pCluster = .1, pFDR voxel corrected = .1, cluster extent = 70 = 0.7 cm3.