Table 4:

Correlations between biomarkers and episodic memory

RAVLT Learning*RAVLT 30 Minutes’ Recall
RR
S1S2S1S2
Hippocampus.49§.70.35.71
A: Middle temporal LH.51.38.33.22
B: Inferior parietal LH.67.44§.48.53
C: Entorhinal LH.66.64.46.64
D: Precuneus (toward isthmus) LH.50.48.15.44
E: Superior frontal LH.43.42.24.38
A: Middle temporal RH.49§.34.16.39
B: Inferior parietal RH.56.49.53.60
C: Entorhinal RH.35.50.23.53
D: Precuneus (toward isthmus) RH.28.54.04.54
E: Superior frontal RH.38.36.29.22
Tau−.28−.60−.09−.73
Aβ42.09.42.33.35
APOE−.09−.17−.34−.18
  • Note:—S1 indicates Sample 1; S2, Sample 2; RAVLT, Rey Auditory-Verbal Test; APOE, apolipoprotein E; Aβ42; amyloid beta 42 peptide; LH, left hemisphere; RH, right hemisphere; R, Pearson r.

  • * RAVLT learning is the sum of correct responses across learning trials 1 to 5. APOE is quantified as the number of ε4 alleles (0, 1, or 2). For tau, cutoff criteria are used in the analyses (0 for nonpathologic, 1 for pathologic), whereas for Aβ42 the actual values are used because only 2 participants in Sample 1 had pathologic values.

  • P < .05.

  • P < .05 when the effect of age is controlled for.

  • § P < .06.