Table 2:

Associations between signal change within DVA drainage region and other factors*

FactorTotalUnadjusted for WM diseaseAdjusted for WM diseaseOR (SE)
Odds (SE)OR (SE)Odds (SE)OR (SE)TotalOdds (SE)
Depth
    Periventricular200.42 (0.21)10.47 (0.25)1130.19 (0.15)1
    Juxtacortical910.10 (0.04)0.24 (0.15)§0.12 (0.05)0.26 (0.17)§670.06 (0.03)0.32 (0.28)
    Subcortical570.09 (0.04)0.21 (0.15)§0.12 (0.06)0.26 (0.18)§450.06 (0.04)0.32 (0.32)
Location
    BG170.31 (0.18)10.29 (0.18)190.12 (0.12)1
    Lobar1260.13 (0.04)0.42 (0.27)0.16 (0.05)0.53 (0.36)940.09 (0.03)0.75 (0.85)
    Cerebellum250.04 (0.04)0.13 (0.15)0.06 (0.06)0.19 (0.24)220.00 (0.00)0
Direction
    Deep680.16 (0.06)10.19 (0.07)1480.13 (0.06)1
    Superficial950.10 (0.04)0.65 (0.32)0.13 (0.05)0.66 (0.34)730.04 (0.02)0.32 (0.23)
    Both50.24 (0.28)1.53 (1.82)0.35 (0.41)1.78 (2.18)40 (0)0
Draining vein
    Long560.15 (0.06)10.17 (0.07)1360.05 (0.04)1
    Medium570.11 (0.05)0.72 (0.42)0.14 (0.06)0.86 (0.52)460.06 (0.04)1.24 (1.18)
    Short530.13 (0.06)0.83 (0.48)0.17 (0.08)1.00 (0.60)430.10 (0.05)2.06 (1.89)
GRE
    No1200.08 (0.03)10.10 (0.04)1910.03 (0.02)1
    Yes40 (0)00 (0)030 (0)0
Malformation
    No1640.13 (0.03)10.16 (0.04)11220.07 (0.03)1
    Yes40 (0)00 (0)030 (0)0
  • Note:—WM indicates white matter; OR, odds ratio; BG, basal ganglia; GRE, gradient recalled-echo; Malformation, associated cavernous malformation.

  • * All DVAs (n = 168); no or minimal WM disease (n = 115).

  • Estimates are not adjusted for other white matter signal abnormality in logistic regression models.

  • Estimates are adjusted for other white matter signal abnormality in logistic regression models. The draining vein is “long” if the depth is juxtacortical and the direction is deep, or if the depth is periventricular and the direction is superficial. The draining vein is "short" if the depth is juxtacortical and the direction is superficial, or if the depth is periventricular and the direction is deep. All others are categorized as "median" draining vein length.

  • § Significant OR with P < .05 using a logistic regression model.