Diagnostic accuracies of metabolite ratios in differentiation of glioblastomas multiforme from aerobic abscesses
| Variable | Accuracy, % | Sensitivity, % | Specificity, % | PPV, % | NPV, % |
|---|---|---|---|---|---|
| Max Cho/Cho-n ≥ 1.05 | 93.3 (76.5–98.8) | 93.3 (66.0–99.7) | 93.3 (66.0–99.7) | 93.3 (66.0–99.7) | 93.3 (66.0–99.7) |
| Max Cho/Cr ≥ 2.31 | 86.7 (68.4–95.6) | 86.7 (58.4–97.7) | 86.7 (58.4–97.7) | 86.7 (58.4–97.7) | 86.7 (58.4–97.7) |
| Max Cho/NAA ≥ 1.65 | 76.7 (57.3–89.4) | 86.7 (58.4–97.7) | 66.7 (38.7–87.0) | 72.2 (46.4–89.3) | 83.9 (57.7–95.6) |
Note:—Cho indicates choline; Cr, creatine; NAA, N-acetylaspartate; -n, normal; PPV, positive predictive value; NPV, negative predictive value; max, maximum. The 95% confidence interval is in parenthesis.