DTI and fiber tracking characteristics of the corpus callosum in control subjects and patients mild TBI who were investigated <3 or ≥3 months posttrauma*
| Control Subjects (n = 10) | Mild TBI <3 Months Posttrauma (n = 12) | Mild TBI ≥3 Months Posttrauma (n = 12) | |
|---|---|---|---|
| Genu | |||
| FA | 0.74 (0.70–0.78) | 0.63 (0.58–0.67)†‡ | 0.70 (0.66–0.73) |
| ADC (mm2/s) | 2.43 (2.27–2.59) | 2.73 (2.55–2.92)§ | 2.53 (2.40–2.66) |
| Fibers (No.) | 495 (442–548) | 522 (458–586) | 460 (407–514) |
| Body | |||
| FA | 0.54 (0.49–0.59) | 0.50 (0.43–0.57) | 0.51 (0.47–0.56) |
| ADC (mm2/s) | 2.71 (2.25–3.18) | 2.77 (2.46–3.08) | 2.65 (2.34–2.96) |
| Fibers (No.) | 254 (221–288) | 218 (179–257) | 225 (197–253) |
| Splenium | |||
| FA | 0.82 (0.79–0.85) | 0.78 (0.74–0.82) | 0.80 (0.78–0.82) |
| ADC (mm2/s) | 2.24 (2.11–2.37) | 2.43 (2.25–2.61) | 2.34 (2.24–2.45) |
| Fibers (No.) | 937 (815–1058) | 877 (761–994) | 1032 (937–1128) |
Note:—DTI indicates diffusion tensor imging; TBI, traumatic brain injury; FA, fractional anisotropy; ADC, apparent diffusion coefficient.
* Values are given as mean (95% confidence interval).
† P < .01, versus control subjects.
‡ P < .05, versus late mild TBI.
§ P < .05.